Zhang Boli appeared, Six Academician attended the meeting, and Chengdu University of Traditional Chinese Medicine released the "Thousands of Materia Medica Projects"

Author:Red Star News Time:2022.07.02

"The research of genome of Chinese medicine has great strategic significance and practical significance. At present, the development of traditional Chinese medicine has encountered two shortcomings. One of them is the decline in the quality of the medicinal materials after the wild transfer, so the research and transformation of medicinal genes is the general trend."

On July 2nd, Zhang Boli, Honorary Dean of the Chinese Academy of Traditional Chinese Medicine and academician of the Chinese Academy of Engineering, appeared at the Chengdu University of Traditional Chinese Medicine to give a speech at the "Thousands of Murled Genome Projects".

For a long time, due to the lack of information on the genome of traditional Chinese medicine base, the lack of communication between traditional Chinese medicine and modern life sciences, emerging cutting -edge life science technology is difficult to apply to traditional Chinese medicine research, which seriously restricts the further development of Chinese medicine.

"From human genome to disease genomics, genomics promotes the progress of modern life science, clinical science, and pharmacy. It is the foundation for promoting medical progress. The modernization of Chinese medicine has brought about fundamental changes and promotion. "

It is understood that the "Thousands of Materia Medica Projects" will provide basic data support for the development of new varieties of medicinal plants, synthetic biology, and the development of localized plants and relocating land protection, and promote the cutting -edge life science and technology Use the application of plants and Chinese medicine to realize the leapfrog development of medicinal plants and Chinese medicine research, helping them to quickly go to the forefront of life science research.

▲ At the press conference site

Chinese medicine genetic resources

Precious national strategic resources

"We will be based on the medicinal plant species collected by China, India, the European Union, the United States, Japan, South Korea, Brazil, Egypt, etc., to systematically collect and organize thousands of medicinal plant resources, build physical libraries, complete more than 1,000 drugs Use plant genome sequence ... "

Academician Chen Shilin led by the "Thousands of Materia Medica Projects" introduced that with the development of modern science, the industry's perception of traditional Chinese medicine has gradually transitioned from early experience accumulation to application modern science and technology in in -depth research on traditional Chinese medicine, but traditional Chinese medicine plants have The understanding of genetic resources is very weak, which will restrict research on the study of the protection of Chinese medicine plant resources, new varieties selection, biological synthesis of new varieties, and pharmaceutical plant model systems.

"The implementation of the" Qianjimu Genome Project "is the only way for the modernization of traditional Chinese medicine. It is to interpret the biological mechanism of traditional drugs to obtain genome and genetic information. The series of problems, including: establish a pharmaceutical model biological system for biological synthesis and regulatory research for secondary metabolic products. By synthetic natural drugs or new drug raw materials for synthetic biological students, use genome auxiliary breeding to cultivate excellent varieties of Chinese herbal medicines, and develop for development. To identify the molecular marking of mixed fakes of Chinese medicine, reveal the nature of the biological nature of medicinal materials, and establish a grass database to protect precious medicinal plant gene resources. "

Throughout domestic and foreign, traditional Chinese medicine genetic resources are precious national strategic resources. "The international competition situation is severe. South Korea, the United States, Japan and other countries have initiated many general genome research in traditional Chinese medicine base species, which has caused great challenges to the field of traditional Chinese medicine research in my country."

It is understood that genes and genome are one of the important strategies of modern Chinese medicine research. The study of biological genetic background research on traditional Chinese medicine is expected to break through worldwide problems such as waste and depletion of resource waste and depletion, environmental pollution and destruction of the modern pharmaceutical industry. Cable, sustainable development and utilization have become the primary problems in the modernization of traditional Chinese medicine in the 21st century. Biology research returning to traditional Chinese medicine species will also become the driving force for promoting leapfrog development in Chinese medicine.

"Thousands of Materia Medica Projects" proposed

Promote the safety of Chinese herbal medicines as national strategic security

At the scene, Zhang Boli commented that the thousands of pharmaceutical plant genome databases in the "Thousands of Materia Medica Projects" will promote the safety of Chinese herbal medicine genes as national strategic security. "Through the research of genomics, we can study the authenticity of traditional Chinese medicine and reveal the drug -effective substances, synthesis laws and mechanisms of the medicinal materials. Studies can also be converted into high -quality Chinese medicine seeds. Drug use, re -dividing the distribution of medicinal materials, especially the artificial cultivation of endangered Chinese medicinal materials. These are the benefits of the grass genome of the grass. "

▲ Zhang Boli

Yu Shuguang, president of Chengdu University of Traditional Chinese Medicine, said that as the first national key discipline of Chinese medicine and the "double first -class" Chinese medicine discipline construction university in the country, it has always been committed to the research and exploration of modernization of traditional Chinese medicine resources and Chinese medicine. The Ministry of Ministry of the Ministry of Traditional Chinese Medicine Resources State Key Laboratory and the National Traditional Chinese Medicine Seed Resource Library. The "Thousands of Materia Medica Projects" led by Academician Chen Shilin will boost the in -depth integration of pharmaceutical plants and Chinese medicine fields with cutting -edge life science and technology to achieve leapfrog and development in the field of pharmaceutical research. New contribution.

In the future, the "Thousands of Materia Medica Projects" will complete the assembly of thousands of medicinal plant genomes, build a major scientific alliance for international medicinal and plant genome, establish China's leading position in the field of international medicinal plant genomes; establish a pharmaceutical plant model research system research system, Promote the research on the synthesis, regulation and transportation of effective components of medicinal plants; establish a database of thousands of medicinal plant genome, and promote the safety of medicinal plant genes to be listed as national strategic safety; build thousands of medicinal plant living resource gardens and seed libraries;Promote the selection of new breeding and effective ingredients of high -quality herbal medicines.Red Star News reporter Liu Kejun

Edit Chen Yixi

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