David Cole: Artificial intelligence combined molecular biology, making tumor treatment more accurate

Author:Changjiang Daily Time:2022.08.05

The Yangtze River Daily Big Wuhan Client August 5th (Reporter Li Qing Wang Chunlan Zou Xunjuan) On August 5th, the 2022 World Big Health Academician Forum was held in Wuhan in the form of the entire line. At the meeting, David Cole, an academician of the British Academy of Medical Sciences and a professor of oncology at Oxford University, said that through artificial intelligence and modern molecular biology, it can provide personalized cancer treatment solutions to prevent cancer more accurately.

Professor David Cole.

Professor David Corge takes bowel cancer as an example. He said that intestinal cancer is one of the most common type of tumor in the world. There are more than 1.2 million patients per year, and about half of them will cause death directly due to bowel cancer.

If the diagnosis is obtained in the early days, patients can surgery to remove primary tumors. Professor David Cole and the team use artificial intelligence and digital pathology to design "digital biomarkers" for patients, predict the possibility of cancer recurrence according to different curves, and provide patients with treatment guidance. For patients with good prognosis, their cancer recurrence and cancer diffusion are very low, and they do not require other treatment after surgery. For patients with poor prognosis, 60%of patients will recur after 5 years of treatment after surgery, so they need to be done just now. At the time of surgery, continued to receive a thorough treatment chemotherapy, which increased the cure rate by 20%to 30%.

"At the same time, we also hope that when using anti -cancer drugs for clinical treatment, we can use 'biomarkers' to predict the benefits of patients." Professor David Cole introduced that if he can develop through research and development of artificial intelligence and molecular biology, The genetic test method to identify high -risk patients can provide patients with more targeted treatment and prevention.

He introduced that during chemotherapy, a few people would have serious side effects, or extend the hospitalization time due to treatment side effects. If a high -risk patient can be screened by gene testing, the dose of chemotherapy can be changed, and then chemotherapy is performed to avoid the pain of patients, toxic and side effects, reducing the burden on the health service system, and allowing patients to spend less money. In addition, people with high risk of intestinal cancer can be identified, and cancer can be recognized as early as possible by regular colonoscopy, thereby cure cancer.

[Edit: Yu Lina]

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