What is the animal living in the laboratory?Reporter takes you to find out

Author:Contemporary health newspaper Time:2022.08.18

In a scientific and innovative building in Jinan City, there are scientific researchers wearing white coats in and out every day. Few people know that some special "residents" -experimental animals here. For ordinary people, the scientific research laboratory is a mysterious place, but in fact animal experiments are closely related to people's lives. When people rest assured to use medicines and be overcome when certain diseases ... Can we think of the role played by experimental animals behind this? As a "alive precision instrument" in life science research, what is the living environment of mysterious experimental animals? Recently, our reporter walked into the Experimental Animal Center of Jinan Central Hospital to find out.

Large mice living in the "VIP" room

When you think of mice, you may have a dark and dirty environment in your mind, but the mice living in the experimental animal center live in the top "VIP" suite in the 10,000 -level purification environment. They breathe the purified air of three -level filtration, and under their feet are loose sterile pads. They eat sterile feed and drinking water. The living environment has standard temperature, humidity and illumination. According to Song Chunhong, director of the Experimental Animal Center of Jinan Central Hospital, the entire facility is strictly constructed in accordance with the national standard GB14925-2010 standards to ensure the reliability and repetitive data of the experiment, which greatly reduces the error caused by environmental factors. In order to ensure environmental safety, it is difficult for ordinary people to enter the living space of experimental animals.

In order to complete this interview, the reporter took a lot of time. At the entrance of the laboratory, the staff put the simple shooting equipment carried by the reporter after three completely disinfection, and then passed through the light passing window. Under the leadership of the staff, the reporter completed the registration, disinfection, and shoes, and wearing a sterile gloves, hats, masks and isolation clothes, passed through the buffer room, and entered the breeding room through a clean corridor -finally saw the "rats of the mice who thought about it. The younger brother ".

In the breeding room, each cage lives with a few mice, sleeping, eating, playing, playing, breastfeeding, etc. "We are now in the barrier environmental facilities. This laboratory is a 10,000 -level purification laboratory constructed by the national standard." Song Chunhong said that the living environment of the "mouse brothers" here reached a state of almost sterile.

Can't blow the wind, can't get rain, eat well and sleep well. Here, it is not exaggerated to say that these "mouse brothers" live in five -star hotels. In the breeding room, the reporter saw a machine similar to a vertical air conditioner is running. "This is the IVC system host." Song Chunhong introduced that the so -called "'IVC system' is the 'independent ventilation cage box system'. Purify the air and purify the air again, and then send it to each cage box. Each cage box has a groaning air outlet, which does not interfere with each other. Each cage is like a "VIP bid room". The results are more conducive to international scientific research exchanges. "Song Chunhong said.

Medical experiments are essential "behind -the -scenes hero"

At present, there are 22 genetic mice and other common product mice and rats in the laboratory. Research. The laboratory is equipped with small animal high -frequency ultrasound imaging systems, small animal metabolism and phenotype analysis systems, behavioral equipment, hematic equipment, frozen slicing equipment, micro -anatomy equipment, animal conventional monitoring and surgical equipment.

The reporter noticed that there were a raised "little pimple" on the back of a few nude rats. These in situ cancer "rat patients" can observe the effect of the drug through regular administration, so as to provide an experimental foundation for the treatment of cancer and new drug research and development.

In the functional laboratory, the reporter saw that the experiments were injecting drugs for mice, and the whole process was accurate and fast, and the mice did not show any discomfort.

As a "living precision instrument" in life science research, experimental animals have made great contributions to human health. Director Song Chunhong told reporters that the hospital established a special experimental animal welfare ethics review committee to check the necessity and scientific check of each animal experiment. "After submitting the experimental plan, after analysis of experts, it must be more profitable to be carried out, and they must review their experimental solutions. You must understand how anesthesia, what anesthesia is, and how to avoid pain during surgery. Ethics, "Song Chunhong said. "April 24th of each year is World Experimental Animal Day. This is a commemorative day recognized by the United Nations. It aims to advocate science and humanity to carry out animal experiments." Song Chunhong said that we must respect life, experiments, animals, animals, animals The experimental center will organize students to carry out commemorative activities on the anniversary and pay tribute to experimental animals who dedicated to life science research!

Comments | Dedication for humans should be respected

There is a mouse monument outside the research facility of a city in Siberia, Russia. The mice in this sculpture wearing glasses, looking forward, holding a sweater needle in your hand, and it is not a sweater, but a "DNA sequence". It looks like a "scholar". In order to pursue technological progress, as early as the 17th century, this rodent animal was used in experimental research. In order to commemorate experimental animals like mice, people sculpt mice to respect.

April 24th is World Experimental Animal Day. This festival is a festival established by the British National Anti -Living Anatomy Association in 1979. It aims to call on the world as an experimental object of animals, which should minimize animal pain and protect the benefits of experimental animals.

Whether it is the establishment of animal sculptures or the establishment of the World Experimental Animal Day, it means that the society is gradually moving towards civilization.

Experimental animals are a relatively special group among animal members. From the day they were born, they were destined to offend themselves as a substitute for human beings. The prevention and treatment of diseases and treatment of diseases can be scientifically taken care of human health.

At present, the experimental animals in scientific research cannot be completely replaced, and what we can do is to provide them with a comfortable experimental environment as much as possible. When experimenting with animals, they are proficient in experimental technology, rationally use anesthesia, and will be used in various links. They will be in all links. The pain is reduced to the minimum, actively discussed the alternative method, reduced or did not use animals to do experimental projects with little significance.

As a healthy guardian, people should respect every life, especially experimental animals dedicated to human health. While enjoying a happy life, we should not forget the dedication and sacrifice of experimental animals.

Reporter: Qiu Tian

Edit: Wang Jing

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