Yao Wenjuan | Disposal science, no regrets cross -border

Yao Wenjuan, who has passed the flower armor, has no traces of erosion on his face. On the day of the interview, as usual, she was holding a neat bun, wearing a simple white shirt, and simply tied a green scarf at the neckline, so that the whole person became delicate.

The School of Mechanics and Engineering of Shanghai University, a professor and doctoral supervisor of the Institute of Applied Mathematics and Mechanics of Shanghai University, has the softness and gracefulness of women -like women in Jiangnan, but her half -life experience reveals the courage and perseverance in the bones: from Chongqing to Jiangsu, from Jiangxi to Shanghai; from structural engineering to fluid mechanics, from solid force to biomechanics ... Seeking half a life, half a lifetime cross -border, each turning is not forced to follow the flow because of the fate, but Yao Wenjuan's determined choice herself. Essence

It is difficult for ordinary people to define which area Yao Wenjuan's research belongs to, but there is no doubt that she is a real person driven by ideals, and a person who is physically and mentally inhabited in the scientific world.

"Science Chinese" seal two characters: Yao Wenjuan

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Break through the comfort zone barrier

Yao Wenjuan is the first college student after resumption of the college entrance examination. It is an educated youth from the city to the countryside after graduating from high school. At that time, the female doll that came out of the countryside was admitted to the structural engineering major of Chongqing University with a perseverance. When she graduated from college, she was 25 years old. After graduation, she joined the work and became home according to the growth trajectory of most people. In January 1982, she returned to her hometown and was assigned to Jiangxi Provincial Transportation Design Institute to engage in structural engineering design and research on roads, water transportation, and house architecture.

Here, she has always been excellent, and she continues to bloom in the design institute: she has presided over three national major engineering projects and provincial and ministerial large -scale key engineering projects, and also presided over a major national project with a single investment of 380 million yuan in 1988 - —— Xinjiang Shipping Engineering Hub Project. During the 10 years of working in the design institute, Yao Wenjuan gradually became the mainstay and the future was bright.

However, when the Tantu spread on Yao Wenjuan, the smooth look at her head made her disturbing. "I have always had a dream of graduate students in my heart."

The age is close, the family is happy, and the career has risen -Yao Wenjuan in the siege keeps asking himself: Is this life? After the child was born, Yao Wenjuan decided to face his inner voice bravely, walked out of the siege, and chased the dream of studying. "The unit has never let me go, they say‘ you do n’t have to study for graduate students. "Yao Wenjuan, who has always decided, decided to leave the relationship with the unit and not pay for a penny to the postgraduate entrance examination. Finally, by relying on the scholarship provided by the Ministry of Education, Yao Wenjuan once again entered the university campus and came to Hohai University to study the number one water conservancy and river dynamics major in the country at that time, laying a solid foundation for fluid mechanics.

Yao Wenjuan, who returned to the academic hall, was unacceptable. Later, she was admitted to the Shanghai Institute of Applied Mathematics and Mechanics to study a doctorate in solid mechanics. "I was 40 years old when I came to Shanghai. For me, I abandoned the work of the original design institute, abandoned the development route that had accumulated in the engineering field, and began to engage in theoretical research from scratch."

Even in the eyes of Yao Wenjuan's relatives and friends, many of her choices are not understood, but she always knows what she is pursuing. On the road to realizing the dream of scientific, she broke through the barrier, and her love in her heart made her life more enthusiastic.

In 1998, Yao Wenjuan entered the Department of Civil Engineering of Shanghai University through talent introduction and engaged in teaching and scientific research. Since then, she officially started her career with theoretical guidance.

Gift

Jiming and even thousands of miles

After coming to Shanghai University, Yao Wenjuan gradually embarked on the road of cross -disciplinary development. The fourth phase of the Shanghai International Shipping Center Yangshan Shenshui Port No. 4 is such a project that allows her to give full play to the advantages of cross -disciplinary background.

In modern society, with the shortage of resources, buildings began to develop to the deep sea. Yangshan Deep Water Port is an attempt to explore and use deep -sea resources, and it is also a major project that has attracted much attention at home and abroad. Such a large -scale deep -sea project with a large and rushing and deep -water foundation has no precedent for the design and construction of high -length and high piles.

"Its pile side rubbing resistance is completely different from our piles. Under the influence of wave circulation loads, the strength of the soil will soften, and there are a lot of stacked in the pier, which will produce a lot of negative motorcycles. In the past, we rely on Zhengmo to rely on Zhengmo The resistance provides a carrying capacity. At this time, if the resistance of the negative motorcycles will not have a large hidden safety hazard, the theory of losing the resistance of the resistance of the motivation is developed. "Yao Wenjuan said that she presided over the" oversized sea industry in the harsh environment of the coastal coastal environment. The theoretical system and computing design method of the structural foundation is super long and high piles. "

In the research, for the actual measurement of the upper softening and deep reinforcement of the super -long and long pile side of the oversized sea industry, it was found that the latest upper softened transmission of the latest upper softened and deep -enhanced load transfer of Yao Wenjuan team proposed the actual conditions of the Yao Wenjuan team. Model. In addition, they also compiled the corresponding computing procedures to solve the problem of calculating computing that universal software could not consider the softening of the soil body around the foundation. By comparison with the measured data, the model calculation results they proposed are relatively previously compared with the actual project, and the calculation accuracy has increased by 20%.

Considering the characteristics of a large number of piles in the port project, the characteristics of the increase in negative motivation on the side of the pile, Yao Wenjuan derived the mission expression of the transition of long piles and the soil and the stress under the pile of piles. Methods and numerical software suitable for non -linear large deformation analysis solves the bottleneck problem of deep saturated soft clay base lack of theoretical support and calculation methods. The above achievements were published in the International Journal of GeomeChanics-Asce (cover article) of the International Geological Journal of Civil Engineering. Yao Wenjuan also developed a model of dynamic response analysis models of deep saturated soft clay super large sea industry under the conditions of service. As a result, it was highly consistent with the on -site test. The paper was published in the international journal "Ocean Engineering" and The TOP journal "Applied Mathematical Modelling" of the Chinese Academy of Sciences solves the power behavior of accurate and effective computing and analysis of the power behavior of the overall sea industry foundation and surrounding soil in the actual project.

Now, the fourth phase of Yangshan Shashui Port has been operating for more than ten years, and the design plan has passed the test of time by the design plan participated in the team of Yao Wenjuan. Among them, her most pleased is that her theoretical research can play a role in such a major foreign trade engineering and go around. She shifted from engineering practice to theoretical research. Now she has feed back the project with her theoretical. This surprise is the best gift for those who are struggling for fate.

Cross -border

The spirit of pioneering the territory

During his tenure at Shanghai University, Yao Wenjuan played the director and participated in the construction of many major projects, including many Shanghai super -high -rise buildings and Donghai Bridge projects, which are well -known at home and abroad. Among them, she hosted the National Natural Science Foundation of China, major national defense research projects, national "15th" science and technology research major project sub -projects, Shanghai Shipping Customs Projects, and application research topics.

After 2000, she published more than 200 academic papers, and more than 100 articles of "Scientific Citation" (SCI) were included; 4 theme and editor -in -chief published monographs; 20 invention patents and software copyrights. The national "Fifteenth Fifteenth" science and technology research topic "Research on Ecological Water Calculation Key Technology", which has been undertaken by her dose, won the second prize of the National Science and Technology Progress Award. The "Introduction to Civil Engineering" edited by the editor -in -chief won the second prize of the National Excellent Textbook Award in 2022.

Yao Wenjuan, who had achieved so many results in the field of structural engineering, did not expect that a chance to turn her research direction again, making her step into the research world of biological structure.

In 2007, a friend who studied at the Five Officials Department of Zhongshan Hospital of Fudan University and raised his confusion to Yao Wenjuan. "At that time, he was studying cochlear structure. He felt that it was difficult to obtain research breakthroughs in research on medical knowledge. The problem he said was related to mechanics. Mechanics was a large branch of physics. I think there are many problems in life sciences. Related to mechanics, and I am academic mechanics. "Yao Wenjuan broke the problem encountered by friends -dynamic issues under the motivation of sound waves. It is also this conversation that prompted Yao Wenjuan to make up his mind again, set foot in the research of the biological field, and open up his own scientific research boundaries.

At this time, Yao Wenjuan, who was already the team leader, was not easy to change the research direction. "Some students are unwilling to do a research on biological structure and just want to do civil engineering research." Even if it is difficult, Yao Wenjuan is still as young as young. At this time, she met her colleagues in scientific research -Liang Junyi and student Ma Jianwei.

Liang Junyi

Liang Junyi graduated from the Department of Physics of Nanjing University. At that time, the physics major of Nanjing University ranked first in the country. Liang Junyi laid a solid foundation there. His research direction was biological physics, which was exactly what Yao Wenjuan was urgently needed at the time. Ma Jianwei is a student of Yao Wenjuan, a student, who shifted from the master's degree in civil engineering to the biomechanical field of doctoral mechanics. They started related research on cochlear active sensing mechanisms.

Break through

Challenge "silent" problem

This is an important practical research.

Deafness is a common human sensory system disorder. There are 360 ​​million people worldwide suffering from deafness. Chinese patients are as high as 27.8 million, and they have increased significantly year by year. Deafness has seriously threatened human health and life. However, hearing reconstruction and restoration have always been an unspeakable issue of human beings.

In order to thoroughly eat this study, Yao Wenjuan had a in -depth understanding of the disease. According to her, deafness is mainly divided into three categories: sensory neuroma, conduction, and mixed, and the sensory neurotrenes accounted for most of them, and the prevalence of 65 -year -old people is as high as 50%. Sensor neurofervant deafness is derived from the abnormality of cochlea, vestibular worm nerve or central hearing system. Among them, the phonetic lesions of cochlear cochlea are the main. This is a disease that cannot be cured so far. Most of the traditional treatment uses auxiliary hearing aid equipment and surgical implanted artificial cochlear cochlear. It can only partially improve the patient's hearing and speech communication ability, and does not realize the autonomous repair of human ear hearing function.

Earlier, Yao Wenjuan's friends were because of the research on the internal ear sensing mechanism based on simple medicine or biological methods, and the characteristics of the flow of flow-electric multi-physical field coupling in the internal ear sensing mechanism were not well understood. Bottleneck. Therefore, she believes that she must start with mechanism analysis, and use multi -disciplinary thinking, based on the principles of biomechanics, biomedicine and medicine, from macro to micro -different perspectives, build a new cochlea model, explore the key of the cochlea sensing mechanism Structure — Base membrane, cover film, and hair cells in electrical and physiological environments The characteristics of the behavior characteristics of the flow-solid-electrical multi-physical field coupling action characteristics of the lymph fluid, so as to recognize the active sensor mechanism of cochlea, fundamentally solve the current cochlear clinical clinical clinical clinical Medical problems. During the research process, Yao Wenjuan's research group cleverly used the multidisciplinary theory such as mathematical physics and biology, and cleverly used the tension mapping method to derive the flow control equation of the lymphatic liquid in the space cochlear cochlear and the base membrane. The real human spiral spiral coleapullane macro structure analysis model and numerical model of the macro structure.

Based on theoretical analysis and numerical analysis, they were pleasantly surprised to find that the macro -supported structure base film of the cochlea has a new motion mode under low frequency -resident vibration (so far no report is seen). This discovery broke through the Nobel winner Golig von Beca Kashi in 1960 to propose the limitations of the theoretical theory of the row motion of the base membrane through experiments, thereby interpreting the low -frequency sensing mechanism and the theory of line wave theory that cannot be explained. Many modern experiments.

For Yao Wenjuan, this is a fantasy scientific research trip. Whenever she finds an incredible phenomenon in the study, she will issue a "signal" to Liang Junyi. "He also do experiments, unlike we only know theory, he often helps me analyze from the perspective of experiments, and inspire me a lot."

At that time, in response to a series of new discoveries, Yao Wenjuan wrote a paper, and also specially invited Liang Junyi to help her write and modify the article. They contributed this research results in "Nature Communications" and passed strict preliminary trials and foreign trials. Lack of experimental data support.

Experiment -this is a major problem that Yao Wenjuan has encountered since interdisciplinary.

Yao Wenjuan, who is engaged in theoretical research, needs to find a unit that can cooperate with experiments. She wanted to wait until the experimental results came out, and still contributed to the "Nature" magazine. Therefore, she saved the papers and never contributed, but did not expect that this is many years. During this period, Liang Junyi went to the University of Maryland to engage in research.

Today, Yao Wenjuan is experimented with cooperation with the Eye, Ear and Throat Hospital affiliated to Fudan University. Although it has not been published in the magazine you expected, this important discovery has won Yao Wenjuan's project on the National Natural Science Foundation of China, "Research on the Characteristic Farm Coupling Active Coupling Active Study in the Conchmann" and the National Natural Science Science Fund key projects "Active Activity Activation Mechanism based on cochlear micro -structural linkage".

In this study, Yao Wenjuan's goal is to use the principles of biomechanics and biological electrical to establish the active cochlear-multi-physical field and chemistry (flow-electronic-chemical) coupling theoretical model that reflects the actual size and physiological characteristics of the cochlea. The real sensation process of simulation simulation cochlea, through the theoretical model's qualitative analysis and the simulation calculation of numerical simulation, realize the base film, cover film, external hair cell body, and static cilia and lymph fluid in the electro -physiological environment Learn behavior and energy conversion law, explain the active mechanism in the senses of cochlea, analyze the effects of inner ear structure trauma and lesions on the hearing threshold of the sensor structure, explore the relationship between the sensory and force-electrical-chemical coupling behavior of the sensor, the maximum Limited to solve the problem of difficulty in sensor neuro deafness.

Obtaining an experimental study of cochlea key macro structure BM's vibration mode in the physiological environment is one of the main goals of the national key project applied for by Yao Wenjuan. To undertake the previous accumulation, the project intends to verify a new mechanism through experiments. At the same time, multi -disciplinary integrated integrated ideas are adopted to establish a multi -structure linkage theory and numerical simulation model of various tissues in the complicated cochlea. The interconnection of structure conversion; explore the relationship between the movement of micro -structures such as base membrane and hair cells and the opening of ion channels, the relationship between membrane protein charges and the motion of coined body electrophoresis; Comprehensively reveal the mechanism of active sensation of cochlea, at the same time provides an efficient and realistic numerical analysis platform for the prediction of postoperative hearing recovery, and provides theoretical basis and application foundation for solving the problem of difficulty in solving the problem of sensual deafness.

At present, this project is still ongoing. In October 2021, the relevant articles of Yao Wenjuan's research group have been published in the International TOP journal of the Chinese Academy of Sciences "Communications in Nonlinear Science and Numerical Simulation."

For Yao Wenjuan, this is a stage summary of her cross -border scientific research. The research is still continuing. Yao Wenjuan is looking forward to the breakthrough in that dream.

grateful

More helpful

Continuously cross -border and innovation, Yao Wenjuan rarely talks about the hardships he experienced all the way, and often mentioned gratitude to the people who helped her. "Although Liang Junyi went to the United States, I often talked to him on WeChat about the progress of the experiment and some problems I encountered. I really want to thank Liang Junyi to bring me a lot of help and inspiration in scientific research. I also want to thank my students that they have made a lot of efforts. "In her heart, everyone worked together to make this study born and continued.

Yao Wenjuan was almost grateful for everyone who had worked with himself.

She is grateful to the Shanghai Construction Engineering Group for her courtesy. She always said: "In fact, compared with the Gong Jian of the Jiangong Group, we do not do it as much as them. They have done so many results transformation. I just did it Some meager jobs. And my student Fang Tingzhang has now become the group's backbone. After entering the group, I also gave us a lot of support and became a bridge between colleges and engineering units. "She also thanked CCCC for the third airline engineering project. Chief Engineer Cheng Zekun of the Survey and Design Institute Co., Ltd., "It has benefited a lot with his cooperation research with major deep -sea engineering."

In terms of scientific research, Yao Wenjuan is most grateful to the support of her leader of the Shanghai University calendar. From the introduction of President Zhou Zhewei, who introduced her to school, to Secretary Jin Donghan who supported her continuously conducting interdisciplinary innovation, and now, she still supports President Liu Changsheng who is still engaged in scientific research and innovation in the year of surgery. "They all pay special attention to talents, and for people of my age, they can also break the concepts and strongly support us to do cross -disciplinary research. It is very rare. Therefore, our school has a very good academic atmosphere."

There are too many people who want to thank Yao Wenjuan. In ordinary people, this seems to be a kind of polite, but communicating with her face -to -face can truly feel the sincerity in her words. She is such a person who never wants to talk about the suffering and glory of her experience, and some of them are just a simple story of scientific researchers, looking back and looking at each other, and gratitude from the heart. Maybe without this usual weight, it is difficult to sit on the cold bench.

Yao Wenjuan finally thanked the person for her mother. "She was from a medical school. When I was a kid, she told me that a person must have an ambition to have a future; a country must have science and technology to be strong. At that time, the ideal of scientific research was in my heart. I want to be an engineer, doctor, and scientist. This ideal has always guided me. "Speaking of which, Yao Wenjuan's smile appeared." I am still realizing this ideal and realized the ideal of becoming a qualified scientist. It's not very complete, but I feel very happy. "At this moment, Yao Wenjuan's eyes are shining because of their ideals.

Expert profile:

Yao Wenjuan, professor, doctoral supervisor. The School of Mechanics and Engineering, Shanghai University, and Teacher of the Institute of Applied Mathematics and Mechanics. Research direction: research on biological structure and engineering structure.

Presides the National Natural Science Foundation of China on the project and key projects; major scientific research projects; the national "15th Five -Year Plan" science and technology research major project sub -project; Shanghai Shipping Customs Project, and application research projects. After 2000, more than 200 academic papers are published, more than 100 articles of "Scientific Citation" (SCI) include 80 articles on "Engineering Index" (EI); 3 international journal cover papers; 20 invention patents and software copyrights.

He serves as the National Natural Science Foundation of China, an excellent youth fund and other reviewers; the editor -in -chief of "Chinese and Foreign Highways" and "Medical Biomechanics", and editor -in -chief of "Journal of Civil Engineering and Construction". He has won the second prize of the National Science and Technology Progress Award, the second prize of the National Outstanding Textbook Award, the third prize of the China Port Science Progress Award, the first prize of the Shanghai Ordinary College Excellent Textbook Award, and the first prize of the Shanghai Teaching Achievement Award.

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