Bull!The invention patent of Hangzhou medicine students may change the surgical method of bladder cancer

Author:Hangzhou Medical College Time:2022.07.26

Bladder cancer is the most common malignant tumor in the urinary system, accounting for the first place in the incidence of urogenital tumors in my country. So far, bladder cancer is the top ten types of cancer in global cancer, accounting for 3%.

The pathological types of bladder cancer include bladder urinary epithelial cancer, bladder squamous cell carcinoma, and bladder adenocarcinoma. Other rare are bladder transparent cell carcinoma, bladder cell carcinoma, and bladder cancer. Among them, the most common is bladder urinary epithelial cancer, accounting for about 90%of the total number of patients with bladder cancer. Generally, the bladder cancer refers to the bladder urinary epithelial cancer.

The most effective way to treat cancer treatment is surgical treatment. Dispeling of bladder tumors (TURBT) of the urethral bladder tumor is the most commonly used surgical method for clinical bladder cancer. However, there are many deficiencies in Turbt. The technical requirements of surgical operations are high. During the operation, bleeding and bladder perforation. Tumor resection on the neck of the bladder and the top of the surgery is difficult to remove tumor resection.

Wang Zancheng, a junior student at Hangzhou Medical College for more than two years, has developed a rotal hard mirror injection needle may solve the above clinical pain points. It is reported that the invention also successfully obtained the national invention patent.

Wang Zancheng led the team members to conduct animal tests

Ear -earned from an early age

Stimulate the curiosity of medicine

Wang Zancheng is a student of the image of Hangzhou Medical College, and his father is an urological doctor. From a young age, Wang Zancheng had a strong interest in medicine.

Since high school, Wang Zancheng has used the holiday time and often follows his father to study at the hospital. His father would also explain the case to Wang Zancheng in his spare time, providing surgical videos for him to learn medical knowledge. At the same time, Wang Zancheng's father will also introduce to him some of the clinical difficulties. These all inspire Wang Zancheng's knowledge of medicine.

When learning about the problems that the bladder cancer may encounter in the operation, Wang Zancheng often hides these problems in his heart. On one occasion, when rotating to the Department of Gastroenterology, the surgery of early gastrointestinal gastric cancer surgery (ESD) was inspired by Wang Zancheng.

Is the non -muscle infiltrated urinary tract epithelial cancer (one of the epithelium cancer of the bladder urinary tract) can also be stripped through the mucous membrane to remove the tumor? This can reduce the difficulty of surgical operations for patients for patients with small trauma and recovery.

But how to achieve mucosal stripping? This has become the main problem that plagues Wang Zancheng. The digestive tract ESD has a supporting hose needle, which can be separated from the base of the gastric tissue through a needle injection separation liquid. However, this set of hose needles appear a bit "stretched" for non -muscle infiltrated urinary tract cancer, because the hose needle can not accurately control the injection range for bladder cancer mucosa, which can easily lead to bladder perforation or damage to other tissues. In addition, the physiological structure of the human urinary system is more direct and simple than the digestive system surgery, and it is difficult to use the hose to cooperate with urinary special equipment such as cystoscopy. Therefore, the idea of ​​developing a brand new high -efficiency and low recurrence of bladder cancer surgery removal of auxiliary needle emerges in Wang Zancheng's brain.

To say it, in 2020, Wang Zancheng completed the designs of hard mirror injection needle draft in a cystoscope and submitted a patent application in that year, but the patent application was not smooth. After many modifications, under the guidance of Professor Wang Lifang, Dean of the Innovation and Entrepreneurship Institute of Hangzhou Medical College, Deputy Dean of Zhang Dahong and his father affiliated to Zhejiang Provincial People's Hospital, this "hard needle" was finally born. In 2022, he successfully obtained the national invention patent.

It is reported that this injection needle is under the hard mirror injection, and the standardized cystoscopy handle is the integrated structure, which is different from the soft mirror injection in the soft mirror in the ESD endoscopic mucosa. The advanced advantage of the hard mirror is that it has strong controllability, simple installation method, accurate injection positioning, and extremely small effects after injection. And can be thoroughly removed in the early stages of bladder cancer, and the quality of prognosis is improved.

According to Wang Zancheng, after the efforts of the team, the equipment has successfully completed several cases of animal ethical experiments, which can raise the animal bladder mucosa layer to remove the tumor. Next, applying for clinical experiments and the transformation of patent transformation into Wang Zancheng will continue to work hard for this.

Wang Zancheng led the team members to conduct animal tests

college students nowadays

Be more responsible on the road of innovation

The university is the ivory tower of many students. Someone here is dedicated, and some people chase their dreams.

When Wang Zancheng is free on weekdays, he will complete the research with Professor Wang Lifang, or follow his father into the clinic.

"Scientific research and professional learning are complementary. How to distribute your time reasonably is very critical." Wang Zancheng said.

According to Wang Zancheng's view, the period of college is no longer a process of simply learning. It can focus on cultivation in many ways, such as innovation. As a student, enrich the knowledge of innovation and entrepreneurship, on the one hand, it is helpful to their professional learning, and on the other hand, it can also stimulate the spirit of college students' innovation and entrepreneurship.

"Now the country encourages public innovation and entrepreneurship. As the main force of innovation and entrepreneurship in the new era, college students need to have more responsibilities. The original intention of innovation and entrepreneurship is to make college students good at discovering, thinking, creating, and continuous contributions to national independent innovation capabilities. Youth power. "Wang Zancheng said.

(Source: Innovation and Entrepreneurship)

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