New strategy for diabetes treatment!"Soil" saves "seeds"

#Diabetes#is a type of metabolic disease characterized by high blood sugar, which is caused by insulin secretion or functional defects. In recent years, the prevalence of diabetes has increased sharply and cannot be cured clinically, which has become a common disease that seriously endangers human health. In the past, he studied diabetes through embryonic stem cells or inductive multi -energy stem cell recycled islet β cells, but faced ethics and tumor risks. Mesenchymal STEM Cell (MSC) can be used to treat a variety of autoimmune diseases, including autoimmune diabetes. In recent years, there have been various MSCs, including PMSC, and differentiated β -like cells that express insulin to treat diabetes. However, people have always ignored the "soil" "soil" pancreatic gland's role in the "seeds" of islets in the treatment of diabetes.

In August 2022, a team of Professor Shi Songtao and Kou Xiaoxing's team of Stomatology Hospital Affiliated to Sun Yat -sen University published a magazine entitled EXOCRINE PANCREAS REGINAL PANCINAL PANCINAL PANCIATE DIABETES of MOUSELS in the Science Translational Medicine magazine. Studies have found that Pancreas-Derived Mesenchymal Stem Cells (PMSC) can be regenerated with the pancreatic gland, and the recovery treatment of the host islets can be proposed for the first time for the first time. The concept of "seed".

The study found that the osteoma-new-born pancreatic glandular glandular glandular glandular gland can be repaired in place of the original exogenous pancreatic gland, improving the inflammatory micro-environment, and promoting islet repair to treat diabetes. /IFN-γ axes to inhibit IL-17. Protecting islets; propose a new concept of local tissue and organ regeneration treatment of systemic diseases.

Extra -regenerative pancreatic gonads under the renal cystic membrane start the original pancreatic gonad, islet recovery therapy type 1 diabetes mode diagram

Professor Shi Songtao, Affiliated to Zhongshan University, and Professor Sun Lingyun, Gulou Hospital of Nanjing University, is the author of this paper. Researcher Kou Xiaoxing is the first and common communication authors in this article.

Original link:

http://doi.org/10.1126/scitranslmed.abg9170

Want to know more exciting content, come and pay attention to BIOART biological art

- END -