Skin itching and skin lesions appear, why do the doctor ask me not to hurt the joints?

Author:Healthy Cantonese Time:2022.06.20

Ms. Wang who was about to retire a few years ago, after a severe cold, a psoriasis -like skin lesions appeared on her body. Ms. Wang has always purchased the ointment to apply it. It has not been treated in a regular medical institution. Recently, Ms. Wang, who is unbearable and severe skin lesions, finally came to the dermatology clinic.

After checking Ms. Wang's skin lesions and nails, the outpatient doctor also asked: "Does your joint feel pain?" Ms. Wang felt a little doubt: "Doctor, knee, finger joint pain for half a year, which has something to do with this disease. Do you think it is caused by high uric acid and rheumatism. "

In the end, after a series of examinations, Ms. Wang was diagnosed with psoriasis arthritis (also known as arthropathy psoriasis). In fact, there are many related diseases for joint damage to skin diseases, such as systemic lupus erythematosus, severe drug rash, and multi -type erythema. Today, I will talk to you about the topic of Taoism arthritis.

What is a psoriasis arthritis?

Psoriasis, also known as psoriasis arthritis (PSA), is a chronic and inflammatory arthritis related to psoriasis. Clinically, it can be manifested as a mononal arthritis or multi -arthritis, and some patients may have sacroiliac arthritis and (or) spinalitis. Attitude, finger (toe) inflammation, and asymmetric oligopolitis are characteristic manifestations of psoriasis arthritis. Patients with psoriasis were mostly hidden, but nearly 1/3 of the patients with arthritis were acute onset. Turks, easy relapse, and arthritis can occur in the late stages, leading to disability. To sum up, patients with psoriasis arthritis not only have psoriasis skin lesions, but also joint damage. Patients with psoriasis may have joint injury risk of psoriasis arthritis (PSA) in the incidence of psoriasis patients with 6%to 13%, European and American reports can be as high as 30%, and psoriasis arthritis is good at age. 30 ~ 50 years old, there is no obvious gender difference. It is worth noting that the incidence of arthritis by psoriasis rises with the proliferation of psoriasis. This suggests that patients with psoriasis should be treated as possible in a timely manner. If the syndrome symptoms should be remembered to the dermatologist, so as not to delay the illness.

Does psoriasis arthritis must be skin lesions first?

The severity of the patient's skin lesions and arthritis is not parallel. 75%~ 84%of patients have skin lesions first, and about 15%of patients with skin lesions and arthritis occur at the same time or arthritis. ), This also caused difficulties in the early diagnosis of psoriasis arthritis. This is why the dermatologist also pays attention to the patient's arthritis symptoms in addition to the skin lesions of psoriasis patients. Similarly, patients with rheumatologists with serum rheumatoids will also pay attention to whether there are psoriasis skin lesions and changes in psoriasis. Because early diagnosis and timely treatment of patients with psoriasis arthritis are essential.

Clinical symptoms of psoriasis arthritis

Artications Psoriasis arthritis joint damage often affects small joints such as joints (toe) joints, palm finger joints, and metatarsal toe joints. Joint and spine. Joint accumulation is often asymmetric, and the joints of the remote fingers (toe) are characteristic manifestations of psoriasis arthritis, and early accumulation of hand joints is more common than foot joints. The clinical manifestation is joint pain, redness, and morning stiffness. Further development can develop different degrees of dysfunction, and even destroy. Skin and A performance (1) Skin manifestations: Psoriasis skin lesions are usually divided into ordinary, pustules and red skin diseases. Psoriasis cortex is an important difference between psoriasis arthritis and rheumatoid arthritis (RA) and other inflammatory arthritis. The skin lesions of various types of psoriasis are not directly related to arthritis. Dedinoma has a certain correlation between the length of the dandruff. (2) Fingers (toe) A manifestation: Refining (toe) armor change is an important characteristic of psoriasis arthritis. About 80%of patients with psoriasis arthritis have finger (toe) lesions and silver without arthritis. Only 20%of patients with crumbs have finger (toe) lesions. Express the diseased lesion of the nail bed. The former includes the separation of nails, excessive lower noria, crack -shaped bleeding, and changes in oil spots. The characteristic performance of the nailing matter is a bit depressed, the white armor erythema and the nails are broken. The proportion of joint suffering from patients A is 43%to 70%, which is the strongest prediction factor for joints of psoriasis patients. Therefore, if a psoriasis patients change A, they should be vigilant and intervene in time. (3) Together: More than half of psoriasis arthritis patients have at least one common disease. Common common diseases include cardiovascular disease, metabolic syndrome (or abnormal metabolic indicators, such as obesity, sugar tolerance, and abnormal blood lipids) , Hyperuricemia and gout, liver disease, inflammatory bowel disease, eye disease depression and anxiety.

Don't worry, don't panic, don't panic

Although psoriasis arthritis sounds terrible

There are also a variety of therapeutic drugs

Treatment of psoriasis arthritis

Non -steroidal anti -inflammatory drugs: Non -steroidal anti -inflammatory drugs mainly play an anti -inflammatory analgesic effect by inhibiting epoxy enzyme activity and prostaglandin synthesis, which can quickly and effectively alleviate the symptoms of joint swelling and pain. Immunosuppressive agent: methotrexate, mulctilizine, pelomin, cycloidin, etc. are traditional changes in the disease anti -humidal drugs. Clinical practice shows that the treatment of arthritis for peripherals peripherals is effective, and there is no obvious in the middle shaft type. Effect. Biological preparations: biological preparations are an effective means to treat psoriasis arthritis, and it is also a powerful weapon for clinicians. Biological preparations can improve the prognosis of arthritis and greatly improve the quality of life of patients. The current clinical biological preparations for psoriasis include TNF-α inhibitors such as Cypa, Berlisab, Ada Mibu, IL-12/23 inhibitors such as Usu Midurate, IL-17A Inhibitors, such as Zikuqiyu, Ichidu Ming, etc., relevant guidelines or consensus and clinical studies at home and abroad have shown the effectiveness and safety of biological preparation treatment. JAK inhibitor: citrus citrate teda was approved by the US Food and Drug Administration for the treatment of adult psoriasis arthritis in December 2017. It is a member of the JANUS kinase (JAK) family member inhibitor, which is suitable for silver Different types of damage of arthritis arthritis. Glycogen hormone: Glycotherapy hormones inhibit the inflammatory response through multiple links. For mononal arthritis/young arthritis, finger (toe) inflammation, and adhesion point inflammation, the internal or tendon sheath injection can be used appropriately. It is generally not recommended for long -term system applications. Traditional Chinese medicine and Chinese medicine: In the activity period, arthritis is mainly caused by damp -heat poisoning and evil puzzle resistance meridians, muscles, bone joints, and skin, corrosive camping blood, and inflow joints. There are two common types of certificates. Therefore, the treatment should be based on clearing heat and detoxifying, and the dampness. last of the last

Please remember ——

If you have symptoms, you must seek medical treatment in time

Scientific treatment, scientific anti -"inflammation"

Source: Guangzhou Health Commission

Edit: Huang Yixin

Editor -in -chief: Wang Hui

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