It reveals the secrets of aging by the largest scale of the aging and longevity of crawled animals and amphibians.

Author:Push medical exchange Time:2022.06.30

190-year-old Jonaton-Seychel Giant Geonathan has recently become news because of becoming the longest-lived landlord in the world. Although evidence like this exists, some types of turtles and other cold -blooded animals have lived for a long time, but the evidence is sporadic, and most of them concentrate on animals living in zoo or a few individuals living in the wild.

Today, researchers from research institutions such as Pennsylvania, Pennsylvania, Michigan State University, and Northeast Illinois University from the United States have reported the most comprehensive research on aging and longevity so far, including from the world, including the world, including the world, including the world. 77 types of climbing animals and amphibians are collected in the wild. Related research results were published in the Science journal on June 24, 2022, with the thesis title "DIVERSE AGING RATES in ECTOTORMIC TETRAPODS PROVIDE Insights for The Evolution of Aging and Longevity".

For the first time, the researchers recorded a particularly low aging rate for turtles, crocodiles, and crickets, and as far as their body type, they had a longer life. They also found that protective phenotypes, such as hard shells of most turtles, help to slow down aging, and in some cases, even "neglecting aging", or lack of bi aging.

David Miller, an associate professor of wildlife population ecology at the common communication author of the paper, said, said, "There are rumors that some reptiles and amphibians are slow and long -lived, but until now, no one has a large scale among many species in the wild. Study this problem. If we can understand what the animals are aging slower, we can better understand the aging of human beings, and we can also provide information for the protection strategy of crawling animals and amphibians, because many of them are animals. Those are threatened or endangered. "

In this new study, these authors will be able to investigate the systematic development methods that can investigate biological evolution to capture animals, mark them, release them back to the wild and observe the marking-re-capture data obtained. Their goal is to analyze the aging and life of cold-blooded animals in the wild, and explore the assumptions related to aging-including the existence or lack of body temperature regulation and protective body characteristics.

Miller explained that the "body temperature regulation mode hypothesis" indicates that cold-blooded animals-because they need external temperature to adjust their body temperature, they usually have lower metabolism-slower than warm blood animals, warm blood animals inside the body in the body It produces its own heat and has higher metabolism.

Miller said, "For example, people tend to think that rats are aging because of their high metabolism, and turtles are slow because their metabolism is low."

Photo source: Photo Network

However, the discovery of these authors shows that the aging rate and life range of cold-blooded animals are much higher than that of the known aging rate and life of constant temperature animals with the same body type, which indicates that an animal regulates its temperature- Whether it is cold-blooded animals or warm blood animals-do not necessarily indicate its aging rate or life.

Miller said, "We did not find such a view, that is, the lower metabolic rate means that the aging rate of cold -blooded animals is slow. This relationship is only applicable to turtles, which indicates that turtles are unique in cold -blooded animals."

Protective phenotype hypothesis states that animals with protection of protective physical or chemical characteristics (such as armor, hairy, shells, or venom) have slow aging and long life. These authors record that these protective features do make the aging speed of animals slower, and in the case of physical protection, they have a lot of life than animals without protective phenotypes.

The author of the paper and the professor of comprehensive biology of Michigan State University Anne Bronikowski, "Said, said," It may be that they have changed their forms, have hard shells, provide protection, and promote the evolution of their life history, including neglecting aging or lack of groups. Learning aging and particularly longevity. "

Beth Reinke, the first author of the paper and the Assistant Professor of Biology, University of Elinois, further explained, "These different protection mechanisms can reduce the mortality of animals because they are not eaten by other animals. Therefore, they are more likely to live alive. For longer, this puts pressure to make them aging slower. We found the greatest support for protective phenotype hypothesis in turtles. This once again shows that turtles are unique as a group. "

Interestingly, these authors at least observe the aging of species in each cold -blooded animal group, including frogs and toads, crocodiles and turtles.

Reinke said, "It doesn't sound exaggerated at all, but basically, once they have passed the reproduction period, the possibility of death will not change with age."

Miller added, "Ignoring the aging of no intention means that if an animal died 1%at the age of 10, if it is still alive at the age of 100, the opportunity to die is still 1%. Compared with 1%. Compared with it. In the following, among the adult women in the United States, the risk of death within a year at the age It happened. "Reinke pointed out that this new study is possible because of the contribution of a large number of collaborators from various species from all over the world.

She added, "I have been able to do these research work for many years and study the authors of their own species. ","

Bronikowski added that "understanding the aging comparison of different animals can reveal flexible characteristics. These characteristics may be proven to be valuable goals related to biomedical research related to human aging."

Reference materials:

Beth A. Reinke et al.divers aging rate in Ectothermic Tetrapods Provide Insights for the Evolution and LONGEVITY. Science, doi: 10.1126/science.abm0151515151515151515151515151515151515151515151515151515151515151515151515

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