Is the deformity sperm related to the malformed fetus?

· Fetal malformations are during the fetal development, due to external factors (radiation, drugs, endocrine abnormalities, infections, etc.), and congenital genetic genetic (such as chromosomal and genetic abnormalities). More importantly, whether the teratogenic factor affects embryos and its degree of impact is related to its time. Within 2 weeks after fertilization, before and after the pregnancy, the impact of teratogenic factors on the embryo manifests as "all" or "none": "full" manifests in the early death of the embryo, and "none" is the embryo continues to develop. Abnormal. Between 3-8 weeks after fertilization, it is the stage of differentiation and development of embryo organs. After being affected by harmful factors, there may be morphological abnormalities and deformities, which are called deformity high-sensitivity period. 9 weeks after fertilization to full moon are the stage of fetal growth, organ development, and perfect function. The sensitivity of teratogenicism during this period is relatively reduced.

· Sperm deformity is evaluated according to the sperm morphology standard in the manual of the WHO semen processing operation manual. It is like a "beauty contest". A normal standard, "ugly" and "distorted" sperm that is not consistent with the standard is defined as deformity. The latest standard of WHO's fifth edition only requires 4%of normal sperm (in popular terms of the average of 4 normal) as soon as possible to make the woman's pregnancy potential. In other words, the sperm deformity rate is less than 96%.

Of course, if the sperm deformity rate is high (> 96%, or the normal ratio is <4%), it can lead to abnormal sperm activity, sperm egg binding disorders, and male infertility. The possibility of embryonic abortion or descendants carry abnormal genes. Therefore, once the sperm morphology indicators are found abnormal, they should be inspected, excluded, and active treatment should be checked in a regular hospital.

Therefore, the sperm malformation rate and embryo deformity are basically two different things, and the two are not necessarily related. Source: Taiyuan Zhongshan Hospital

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