In the 30s, the heart is not good, beware of the premature failure of the brain!

Author:Journal of China Science Time:2022.08.25

Text | Li Muzi

Recently, "Liuye Knife -Health and Longevity" released a report that people with poor cardiovascular health at the age of 36 predict that their brain will be greater in the future, and men's brain age is often greater than women of the same age.

The older a person's brain, the lower the cognitive ability test score, and in the next two years, brain atrophy will increase. This may be an important clinical symbol of cognitive ability or other people with brain -related disease risks.

"We found that although the real age of the people participating in this research is very similar, the computer model predicts that there is a big difference in age of their brain." Jonathan Schott, a professor at the Symptom Research Center, said, "We hope that this technology can one day a useful tool for identifying people with accelerated aging, so that they can adopt targeted prevention strategies as soon as possible to improve their brain health."

Researchers use MRI -based machine learning models to estimate the brain age of the Insight 46 research members funded by the Alzheimer Disease Research Center in the United Kingdom. The research is led by Schott. Insight 46 is a sub -research of the National Health and Development Survey of the Medical Research Committee, and the latter is also known as the British birth queue in 1946. As participants are part of this study throughout their lives, researchers can compare their current brain age with various factors in the entire life process.

Participants are between 69 and 72 years old, but their brain age is estimated to be between 46 and 93. By reviewing various factors in the entire life process, researchers can explain the age changes of about 1/3 of the brain.

At the age of 36 or 69, people with poor cardiovascular health are also poor in brain health. The same is true of MRI (related to cerebral blood flow and vascular). This is consistent with a previous study of Schott. The study found that high blood pressure at the age of 36 indicates that the brain health is poor in old age.

The study did not find any connection between children's cognitive functions, education levels, or social and economic status and premature aging of the brain.

Researchers also found that the older the brain, the higher the concentration of nerve mild protein (NFL) in the blood. The elevation of NFL is considered to be caused by nerve cell damage, and it is increasingly considered a symbol of neurotherapy.

Dr. Sara Imarisio, the head of the Alzheimer Disease Research Center in the United Kingdom, said, "The research of Insight 46 helps to reveal more complex relationships between people's brain health." By using machine learning, this study found that it was found More evidence, indicating that the poor health status of middle -aged heart is related to the more severe atrophy of the brain in his later years.

Related thesis information:

http://doi.org/10.1016/s2666-7568 (2)00167-2

"China Science News" (2022-08-25 2nd Edition International)

Edit | Zhao Lu

Capture | Zhihai

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