Known as the "worst mutation strain", how much harm is Beijing and Xi'an's new strain BA.5?An American patient infected with a new crown for 471 days, and the virus mutated in the body 3 times

Author:Shanxi Evening News Time:2022.07.07

The continuous mutation of the new coronal virus has brought new challenges to the prevention and control of the epidemic.

In the past few days, in many places, the local epidemic was reproduced. In Xi'an and Beijing's Xinfa epidemic, the virus gene sequencing of the infected person pointed to the more spreading Omikon BA.5.2 branch.

According to the Science and Technology Daily, industry experts said that, in addition to faster transmission and higher virus load, the new branch of Omikon mutant strains has appeared in the previous mutant strains of Omikon. The new situation of strong immune escape ability may increase the rate of severe illness.

In the United States, a study has once again refreshed people's virus cognition. According to the latest report, a new crown in the United States was infected for 471 days, and the virus mutated 3 times in the body.

New poison strains land in Beijing, Xi'an

On July 6, there were three newly reported local diagnosis cases in Shaanxi, and 1 asymptomatic infected were in Xi'an. Earlier, from July 2nd to July 5th, 29 newly infected people were added in Xi'an in 4 days.

In order to calm the society as much as possible, reduce social liquidity, quickly find out the potential source of risks, and reduce the risk of cross -infection, Xi'an announced that from 0:00 on July 6, the city has implemented 7 days of temporary management and control measures.

On the 5th, a press conference on the prevention and control of the new crown pneumonia epidemic in Xi'an: The results of the gene sequencing showed that the strains that caused this round of epidemic were all Omicron mutated strains BA.5.2. The virus branch comes from abroad, but the source is not clear. Compared with other popular mutant plants, the spread of BA.2, which has caused the surge in local cases at the beginning of the year, has a faster speed and strong contagious. It is not ruled out that a new communication chain will appear in the future, causing the community to renew the risk of renewal of communication.

According to Xi'an's notification, most of the positive infected people currently discovered are related to waste recycling personnel or their relevant personnel. Most of the positive infected people have the history of contact and living together.

At the press conference of the Beijing New Coronatte Pneumonic Pneumonia Epidemium on the 6th, Pang Xinghuo, deputy director of the Beijing Centers for Disease Control and Prevention, introduced that the Beijing Centers for Disease Control and Prevention was reported to the infected person reported on July 5 The specimen was generated by the specimen, and the results showed that the virus belonged to the BA.5.2 branch of Omikon. The results of gene sequences showed that the three infections were low as Beijing's existing and previous local cases, and low input case sequence sequences in the city, which was low, and was a different transmission chain. Comprehensive epidemiological survey and gene sequencing results, initially considered the local clustering epidemic caused by this epidemic.

Yesterday (July 6) at 0-24, 32 cases of new local new coronary pneumonia were added and 22 cases of asymptomatic infection were added, of which 30 confirmed cases and 22 non -symptoms were found in isolation control.

Is there a BA.5 mutant strain in Shanghai?

In the "Shanghai release" WeChat public account, some netizens in the comment area asked: Isn't it BA.5 strain?

In response to this "Shanghai release" response: As of now, the results of the complete virus gene sequencing show that no BA.5 mutant strains were found, all of which were BA2.2.

Ba.5 "Retos" infection with lung ability

Or increase the severity rate

Since December last year, the new crown virus Omikon mutant strain has become the main popular strain in the global new crown pneumonia. With the continuous evolution of Omikon's mutant strains, the WHO will 6 species on May 18 this year this year. The sub -branch of the Omikon mutation strain is listed as "the proprietary device in the monitoring", including 4 sub -branches of BA.4, BA.5 and BA.2.

On May 30, the China Centers for Disease Control and Prevention released an English Weekly report that China has found the first infection of the first new crown virus Omircoro's Omicoro mutant in overseas.

Weekly reported that the case departed from Uganda on April 25, transferred in Amsterdam on the 26th, and transferred in Seoul, South Korea on the 27th. The patient had vaccinated 4 doses of new crown virus vaccines in China and Uganda. After the diagnosis, the patient was transferred to the Shanghai Public Health Clinical Center for treatment. After recovery, he was discharged from the hospital on May 12.

On May 13, the patient's nasopharynx swab (collected on April 29) accepted the genome sequence, and the results showed that the patient infected the new crown virus Omikon BA.5 mutant strain.

The gene sequence of BA.5 was first uploaded on March 15, 2022, from the nasopharyngeal and oral pharmaceutical swabs from a patient collected on February 25, South Africa. With BA.4, the BA.5 mutant strain has led to the growth of the epidemic in South Africa in recent weeks, and spread to other 19 other countries within 3 months.

Eric Topol, the director of the SCRIPPS Research Institute (SCRIPPS Research), is a medical expert who has long been concerned about the new crown epidemic. The worst version in the plant. It has reached a new level that has existed widely immune escape, and enhanced the infection, far exceeding the Omikon mutant strains we have seen before. "

Industry experts said that, in addition to the faster transmission and higher virus load, the new branch of Omikon variants BA.5 has appeared to invade the lungs and has strong immune escape ability compared to the previous mutant strains of Omikon. New situations may increase the rate of severe illness.

On July 6, residents of a community in Xi'an lined up for nucleic acid testing

An immunologist said: Those who have been infected with the new crown virus will still be infected with BA.5 again. In addition, the impact of BA.5 on lung function will increase close attention. Li Kefeng, associate professor of the Medical Center of the University of California, San Diego, explained that the previous original strains could use alveolar cells to invade human lungs with protein that did not go up the respiratory tract to increase the risk of severe illness. The infection is up to the respiratory tract, and BA.5 retrieves this ability and "regain" lung infection.

A new crown in the United States is 471 days long

The virus varies 3 times in the body

In the United States, a news refreshes the cognition of people's viruses again.

According to the overseas network quoted the New York Channel of the United States Broadcasting Corporation, a new study at Yale University showed that a cancer patient in Connecticut in the United States was infected with a new crown virus for 471 days. During this time, the virus mutated three times in his body.

The report said that in the regular monitoring of the new coronal virus variant, they found that B.1.517 mutant strains appeared in Connecticut, and this variant had disappeared around the world for a long time. Through tracking, the research team found a 60 -year -old lymphoma patient. The patient first detected the positive of the new coronary virus in November 2020, and the test results of the test in March 2022 were positive.

"Within 471 days after the first diagnosis, the patient's new crown test results have been positive." The report added that the patient was contagious and basically had high virus load during this time. In addition to long -term infection, this research team also noticed that over time, the new crown virus rapidly mutated in the patient's body, and even three different new variants appeared. The report states that the variation speed of the new coronal virus in this patient may be twice the speed of mutation in ordinary people.

The US Centers for Disease Control and Prevention said on July 5 that within the 2nd week, 70.1%of the new crown cases in the United States were caused by the mutant strain Omikon BA.4 and BA.5 subtypes.

Reuters quoted data reports of the US Centers for Disease Control and Prevention. In the national diagnostic cases, the proportion of pathogens caused by BA.4 and BA.5 were 16.5%and 53.6%, respectively. In the week of June 25, these two new subtypes accounted for more than 50%, while this proportion in early May was only 1%.

"American News and World Report" reported on the 5th of this month that about 100,000 new crowns have been added in the United States in the past and a half months, but in view of BA.4 and BA.5 subtypes, strong infectious, short latent periods, transmission periods, spreading, and communication The proportion of fast speed and asymptomatic infection, many people think that real numbers may be higher than this.

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Source: Shanxi Evening News All -Media Comprehensive

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