The magical "artificial liver" saves people in crisis -Xianyang No. 1 People's Hospital allowed the "Little Yellow Man" to successfully exchange skin

Author:Xianyang from all walks of lif Time:2022.07.16

Liver cirrhosis, the 52 -year -old man becomes a "little yellow man"

The 52 -year -old uncle Wang was annoyed in the first half of the year, but the hospital was annoyed. In March, he began to have symptoms of abdominal distension and visited local hospitals to improve the diagnosis of liver cirrhosis (liver dysfunction period) after improving the relevant examination. In mid -June, he once again appeared in the skin's skin mucosa and sclera yellow stain, which became a "little yellow man". At the same time, it also appeared symptoms such as skin itching, nausea, vomiting and other symptoms. Faced with the worsening condition, Uncle Wang's family decided to go to the local hospital again. The admission of liver merit was inspected, and the total bilirubin was as high as 348.2 umol/L. The total bilirubin reference value of normal adults was 3.4-17.1 microl/liter, which means that his inspection value is close to 100 times that of normal people. Direct bilirubin 243.7 umol/L, indirect bilirubin 104.5umol/L, Tianmen Winomine-based metastases 364IU/L, Alanine aminotransferase 484IU/L, weight decreased by 4-5 pounds than before.

"Looking at his weakness and soft paralysis on the bed, the jaundice is getting heavier, and we can't eat it. We are anxious but helpless." The family members were almost desperate. The local hospital recommended him to go to the city of the city.

After entering the hospital, the patients are given to patients with liver preservation, drug retreating, fluid, and correcting electrolyte disorders. The effect is not good, the bilirubin continues to rise, the patient's spirit is extremely poor, it is almost impossible to eat, repeated nausea, vomiting, the situation of consciousness is poor The family members are very anxious, what should I do? Division of Yuan Ya, deputy director of the Department of Severe Medicine, met with a closer look and inquiring about the medical history: If the bilirubin continues to rise and does not decrease, the gallblade encephalopathy may appear coma or even life -threatening.

"Artificial Liver" treatment effect is significant

On June 22, the patient was transferred to the ICU further diagnosis and treatment. After the enrollment, Guo Haocha, the director of the subject, looked at the patient and confirmed that the patient needs to reduce bilirubin as soon as possible and strengthen the liver preservation. Extraine adsorption therapy. Through the "artificial liver" technology, it can avoid further damage, which is conducive to the repair of liver function. Unlike traditional treatment methods, the artificial liver support system can temporarily replace the various functions of damaged liver "exercise", including clearing jaundice and toxins in the liver, supplementing coagulation factors and protein that requires the liver itself. After finding a new treatment method, Uncle Wang's family's hanging heart finally let go.

Medical staff actively accompanied by the same plasma, intravenous venous puncture tube, and CRRT tubes on the machine; after about 3 hours, it was accomplished with blood, and plasma replacement+bilirubin adsorption therapy was reviewed the next day. The situation improves, nausea and vomiting decrease.

After three days of plasma replacement+bilirubin adsorption therapy, the patient's liver re -examination indicators have improved significantly, liver power: total bilirubin 240 umol/L, direct aprochin 161 umol/L, indirect bilirubin 78umol/L/L , AST159IU/L, Alt 127IU/L. The mental condition has improved significantly.

This technology is the mature technology of severe medical science in Xianyang First People's Hospital. It has carried out various treatment modes such as plasma replacement, DPMAS (dual -heavily plasma molecular adsorption system), DPMAS+semi -amount plasma replacement, bilirubin adsorption, plasma irrigation, CVVH (continuous continuous Sexual vein blood filtration), CVVHD (continuous vein-venous hemodialysis), CVVHDF (continuous venous-venous hemodialysis filter), etc., solve the emergency of patients with acute and chronic liver failure. (Yuan Yaying reporter Han Yongguo)

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