The development and utilization team of the Food Resources of the North Academy of Sciences The Drug Resource Development and Utilization Team has made new progress in the research on the synthesis of cordyceps in Cordycestine

Cordyceps Militaris is an important traditional food bacteria in my country, including polysaccharides, cordyceps, Cordycele acid (mannitol), oleanol, adenosine, N6- (2-hydroxyeyl) adenosine (HEA), etc. Rich biological activity ingredients. Cordyceps is one of the important active ingredients of Cordycestine. It has a variety of biological active effects such as anti -tumor, treating leukemia, regulating blood sugar, anti -hyperlipodia, and antiviral virus. Beijing Institute of Science and Technology Research Institute of Radiation Technology Institute of Food and Drug Resources Development and Utilization Team adopted ion beam into mutaged and selected high -produced cordyceps cordyceps strains to obtain strains with an increase in cordycele production by 8.85 times Two, published 9 academic papers.

Figure 1 Screening of High Cordyceps Cordyceps strains

On this basis, Dr. Liu Guijun tapped and compared the metabolic products of cordyceps cordyceps cordyceps, low cordyceps strain and the metabolic products of the strain, and found that the key compound adenosine, AMP, ADP-nucle sugar, and 3 'in the synthesis of Cordyceps slices were found -AMP, etc., by analyzing changes in the relative content of the above compounds in the three strains, improved the prediction of Cordyceps synthesis pathway, and provides a scientific basis for the analysis of the synthetic pathway of Cordyceps. At the same time, it was found that high -producing cordylin pupae strains are also high -yielded anti -cancer drugs "sprayed him". This discovery effectively enhances the development and utilization value of the strain, and will be combined with the characteristics of the cordyfiliac strain to carry out health products development research. The research results of this part of the research results "Research on Cordyceps Cordyceps Cordyceps Box Synthetic Path" has been accepted by the domestic CSCD core journals. To.

Figure 2 Cordyceps strains Different Metabolic Models

This research work has received funding support from the special topics of reform and development of the Beijing Institute of Science and Technology. In the next stage, the development and use of the team scientific researchers will continue to optimize the fermentation process of food bacteria, the extraction and purification of activated compounds, and the metabolic regulatory regulation of the synthetic pathway to speed up the development and the development of health resources and health products Promotion and application.

(Institute of Radiation Technology)

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