The new technology of Zhengdayi Affiliated Hospital fills in domestic gaps

Author:Medical Health News Time:2022.09.19

(Reporter Chang Juan Correspondent Zheng Xiaohan) Han Xinwei, director of the radiation intervention department of Zhengzhou University First Affiliated Hospital, adopted the independent developed iodine-125 particle ureteral stents to successfully treat patients with refractory hematuria caused by elderly ureter tumors. It is reported that the technology uses a stent to relieve ureteral obstruction and carry particles with particles to treat tumors in order to control tumors to eliminate hematuria. It is still the first in China.

Not long ago, 75 -year -old Mr. Li held the banner and pulled Han Xinwei's hand, and said excitedly: "Thank you for your new technology, let me keep the kidney and solve the problem of hematuria."

Mr. Li has repeated hematuria in recent months. Magnetic resonance shows the dilated water of the right renal pelvis and the upper middle section of the ureter. It is suspected to be the tumor of the ureter. The treatment plan given by the local doctor is to remove the right kidney, ureter and some bladder. However, Mr. Li was implanted with 3 stents in coronary heart disease half a year ago. He had a poor score in the heart of the heart and could not tolerate systemic anesthesia and major surgical treatment. This is how to do? After turning to many hospitals, Mr. Li found Han Xinwei.

After a detailed understanding of Mr. Li's condition, according to the special circumstances of the patient, Han Xinwei's team decided to use independently developed iodine-125 particles of ureteral recyclable bracket treatment. This technology can avoid both kidney, ureter, and some bladder resection, but also use particles to treat tumors to control hematuria. The stent can exert the drainage effect to relieve the accumulation of the kidney, and finally achieve the cure effect.

In recent years, radioactive iodine-125 particle implantation technology has developed rapidly at home and abroad. The iodine-125 particles belong to the micro radiation source of low-radiation agent quantitative rate. After implantation of the tumor, X-rays and γ-rays can be continuously released. Tumor cell proliferation, lively tumor cells, reduce tumor control tumors, and reduce the recurrence and metastases of tumors.

At present, patients with prostitution, recurrence, or metastatic vicious physical tumor, such as prostate cancer, lung cancer, liver cancer, gastric cancer, pancreatic cancer, etc. are suitable for implantation of radioactive particles. Radial iodine-125 particles have the following advantages in the treatment of ureteral tumors: in the tumor segment ureteral accuracy of particles in the scientific plan, through continuous close-range irradiation to completely kill the tumor cells, and the damage to the surrounding normal tissue is minimal; It is suitable for a small spatial structure of the urethra, which is convenient for operation; close -range radiotherapy, related toxic and side effects are very small, and patients are happy to accept. Based on this, can the radioactive particles combine with the existing ureteral stent to create a functional ureteral stent?

Han Xinwei and Zheng Dayi Affiliated Hospital Dr. Jiao Dechao's clinical needs have successfully developed a number of national patents on the basis of successfully developing the iodine-125 particle biliary drainage pipes in the early stage. In conversion, ureteral stents that can carry iodine-125 particles have been developed to fill the gaps in the domestic field.

According to Jiao Dechao, this new type of ureteral stent that can carry iodine-125 particles can be placed in the obstruction of the ureteral tumor through a minimally invasive intervention or endoscopic adverse row in the bureau. Give full play to tumor radiotherapy that continues to be close to each other, and can be used for patients who cannot undergo surgical surgery, ureteral malignant obstruction of elderly patients, patients with repeated hematuria of ureteral tumors, and patients with strong willingness to protect the kidneys.

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