Cef+wine, how much will drink?99%of people can't think of

Author:Health circle Time:2022.07.22

On July 20, the article "New Yellow River" showed that after a young girl quarreled with her boyfriend, she bought 10 online listening to beer and a box of cephalosporin online in the middle of the night.

Fortunately, the careful takeaway brother found abnormalities and called the police in time to avoid a tragedy.

"Cephalosporin with wine, just leave."

Everyone has heard of this, knowing that these two things cannot be eaten together.

However, why is cephalosporid+wine poisoning?

After taking cephalosporin, how much wine will you really live?

How many days do you take medicine and drink?

01

Acetaldehyde accumulation causes poisoning

The metabolic process of alcohol in the liver is:

Ethanol → acetaldehyde → acetic acid → carbon dioxide and water.

Among them, the toxicity of acetaldehyde is said to be 10 times that of ethanol.

Some cephalosporin drugs can inhibit the liver's acetaldehyde dehydrogenase, block the further transformation of acetaldehyde to the acetic acid, and accumulate a highly toxic settown in the body, which causes a series of poisoning reactions (medical called bisulfate Lun -like response).

The main manifestations are redness, headache, nausea, vomiting, blurred vision, decreased blood pressure, accelerated heart rate, chest tightness, and difficulty in breathing. Severe respiratory failure, myocardial infarction, and even death will occur.

The severity of this poisoning reaction is related to the dose and drinking of the drug.

The higher the drinking alcohol content, the heavier the reaction; drinking during the medication, the heavier response than the drinking after stopping.

02

The famous doctor almost killed

Professor Ling Feng, chief expert of Xuanwu Hospital of Capital Medical University, once shared his personal experience in the "Medical Community":

One morning, she took a piece of "cephalosporin ester". In less than two minutes, she felt itchy, then dizzy, lost consciousness, sweaty, and her limbs were cold. Fortunately, they were taken to the hospital for rescue. Return to life.

Professor Ling Feng, Chief Expert of Xuanwu Hospital of Capital Medical University

Afterwards, she recalled that she drank half a glass of red wine when she attended the dinner day before yesterday.

Professor Ling Feng believes that it is the humble half -glass of wine, and a piece of "cephalosporin ester" taken on the next morning, which produces a serious poisoning reaction, almost let her destroy Huang Quan.

03

Stopping the medicine for 4 days is still poisoning

Professor Ling Feng was poisoned the next day after drinking alcohol. So how many days to take medicine and drinking, can you be poisoned?

The outpatient department of the Handan Handan Sanxiu Institute and the Navy's 91451 Troops analyzed the case of the 12 oral cephalosporin antibiotics they received.

The amount of drinking of cases is up to 400 ml, and only 50 ml of less.

Among them, there were 10 cases of drinking on the day of the medication, and there were 2 cases of drinking for 2-4 days.

This shows that drinking on the day of medication is the easiest to poison;

However, even if it is not drinking on the day of the medicine, it will still be poisoned after drinking the medicine for 4 days.

04

Wife murded his husband

Taking cephalosporins and wine can make people poisoning. After understanding such knowledge, ordinary people's reactions are to avoid doing so and not let themselves be trapped in danger.

However, some people moved another mind.

At the beginning of this article, the girl intends to look at the short -sightedness.

What's more, I really want to use this method to murder the lives of others.

In April 2022, the People's Court of Zhengyang County, Henan Province announced a criminal incident:

The 50 -year -old woman Huang Moumou, in order to achieve the purpose of living with her husband, even put the cephalosporid drugs in her husband's diet when she was drinking alcohol, and wanted to cause her husband to die. Fortunately, she did not succeed.

The woman and lover were sentenced to 2 years in prison for intentional homicide.

05

Seeking to see a funeral hospital after drinking

The Henan woman did not succeed. Maybe she didn't know how much alcohol had to drink to have a fatal poisoning effect with the cephalosporin.

Regarding this issue, there is no clear consensus in medicine.

However, the two real deaths revealed the answer worthy of reference to a certain extent.

The 43 -year -old Hu had a head injury after drinking, and went to the hospital for treatment. Unexpectedly, a large number of vomiting, dyspnea, and lips were dazzling during the infusion process.

Forensic doctors believe that Hu's cause of death is to "cephalosporin" by intravenous after drinking, causing a poisoning reaction and leading to acute heart failure.

The test results showed that the ethanol content in Hu's blood was 125 mg/100 ml, reaching the traffic police department's judgment standard for "drunk" driving (80 mg/100 ml).

Such drinking volume is obviously relatively high.

The higher the amount of drinking, the more severe the poisoning reaction. Even at the time of the incident, Hu was at the hospital and could not get rid of the magic claws of the gods.

06

A bottle of beer can be fatal

However, the amount of drinking is relatively low, and it may not be poisoned.

The 56 -year -old Jing was uncomfortable after drinking. After getting medicine at the clinic, he had difficulty breathing after taking medicine. He was sent to the hospital to rescue and died.

The forensic doctor found that he died suddenly after drinking the antibacterial drug "amoxicillin" capsule.

Unlike the above, the concentration of ethanol in Jingmou's blood is only 12.9 mg/100 ml, and it has not even reached the minimum value of the "drinking" driving judgment standard (20 mg/100 ml).

According to calculations, in general, after drinking 350 ml of beer (equivalent to 1 small bottle) or semi -white wine (20 ml), the alcohol concentration in human blood can reach 20 mg/100 ml. In other words, even if you only drink a small bottle of beer or half of the white wine, if you take the common drug "amoxicin", it will make people lose their lives.

Such a common amount of alcohol plus drugs will have such serious consequences, which exceeds the imagination of many people.

It can be seen that when alcohol and drugs are mixed, even if the amount of alcohol is very ordinary, it is not safe.

07

The danger is not only cephalosporin

Professor Ling Feng, chief expert of Xuanwu Hospital, Capital Medical University mentioned earlier, has told people to learn their painful lessons after experiencing ghost gate, and do not repeat the same mistakes.

She reminded that the following drugs are easy to cause poisoning reactions with alcohol:

Cephalosporin drugs: cephalosporidone, stretching cephalosporin, cephalosporin, cephalosporin, cephalosporin, cephalosporin, cephalosporin;

Intidazole drugs: metronidazole, tinidazole, amuolizone, etc.;

Drugs and foods that will cause poisoning (Source: Research Thesis)

Professor Ling Feng suggested that alcohol should be banned 2 days before the use of the above drugs, and drinking alcohol should be avoided one week after medication, or drinks and medicines containing alcohol, including wine -hearted chocolate, Huoxiang Zhengqi water, etc.

Similarly, if you drink, you cannot take cephalosporin and imidazole drugs within 1 week.

The poisoning reactions produced by these drugs and alcohol, including the following symptoms:

Limb weakness, weakness, drowsiness, dizziness, hallucinations, headaches, nausea, vomiting, chest tightness, redness, collapse, convulsions, even blood pressure decreased, respiratory suppression, shock and other reactions.

Those who are light can relieve themselves, and those who are serious should be sent to the hospital for treatment in time.

A healthy body is incredible for many people. We should cherish it. Do not do stupid things like "cephalosporin".

At the dinner, what should I do if I still know that I have eaten cephalosporins.

A netizen gave a wonderful suggestion. You can take out the cephalosporin and hand it out for the other party: Otherwise, you can eat it, and then let's drink together?

Reference materials:

[1] Chen Xueling, & Xiao Xiao. (2020). The research status of the dialogo -like reaction and the diagnosis of forensic medicine. China Legal and Medicine Magazine, 35 (4), 4. 4.

[2] Liu Yuqi, & Meng Yan. (2016). After oral cobe antibiotics, they drink and drink twelve clinical analysis.

[3] Zhang Jianhua, Li Wenzhan, & Chen Yijiu. (2015). Intravenous drops of cephalosporin reacting 1 case of death.

[4] Dong Huangyong. (2016). Patients with coronary heart disease reflected in the analysis of death.

[5] Ling Feng, how terrible to eat cephalosporin after drinking? Intersection Doctor Ling Feng's life and death 24 hours, medical community, 2019.5.21

Author: Dongdong | Editor: Bu Guli 涫涫 | Review: Lao Bai

Image source PEXELS picture network, infringement deletion.

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