Wu Lianfeng, a special researcher at the School of Life Sciences, West Lake University: Public enemy who sters human health in difficulties

Author:Zhejiang Daily Time:2022.09.28

2022-09-28 11:48 Zhejiang Zhejiang News Client reporter Dai Ruiyun 52,000+Reading

Reporter Wei Zhiyang photographed friends Ma Chongyan

"It is said that the basic scientific research work is very mysterious. In fact, our work is very grounded. For example, we are exploring every day and how does diabetes that plague hundreds of millions of people happen?"

Wu Lianfeng, a representative of the 20th National Congress of the Communist Party of China and a special researcher at the School of Life Sciences at the University of West Lake University, was busy in the laboratory.

Diabetes, cancer ... These metabolic disease -related diseases are public enemies of human health. Starting from the mechanism of molecularity, unveil the mystery of how these diseases occur, and find the medicine that is more perfect -scientific and technological workers in the world of life sciences and the direction of Wu Lianfeng challenged.

"It is the mission and value of basic scientific researchers." Wu Lianfeng diligently asked for a better way to continue the research ideas of metabolism and aging, trying to find a better way to sniper -related diseases, and hoped to overcome metabolic -related diseases as soon as possible.

Reporter Wei Zhiyang photographed friends Ma Chongyan

Wu Lianfeng has an impressive academic resume. After graduating from the Biotechnology of Biotechnology at Huazhong Normal University in 2005, he was sent to the Institute of Biology of the Chinese Academy of Sciences and obtained a PhD in Science in 2010. In 2011, he went to Harvard Medical College Massachusetts General Hospital for postdoctoral research and returned to the former lecturer of the Department of Medicine at Harvard Medical College. In 2017, the destination of Wu Lianfeng returned to work was the West Lake Higher Research Institute, formerly known as the West Lake University.

Give up the stable work of the world's top medical school, take the family to Hangzhou with the whole family, and join the new research university -many people think that Wu Lianfeng's choice is a bit "impulsive". "Actually, from the moment of going abroad, returning is the unchanged decision." Wu Lianfeng said that the heart of returning to China has never shaken.

Walked by the famous scientist Shi Yigong and others, the West Lake University, which refers to the cutting -edge science and technology of the world, must "let more world -class results come from the laboratory in China and let more world -class scientists come from Chinese universities" - — Seeing the recruitment of the University of West Lake, I saw the sponsor is a leading scientist in the global life sciences. Wu Lianfeng's eyes brightened: This is the long -lasting Chinese scientific research platform.

In the past five years, it is the five years of West Lake University's "from scratch", and it is also the five years of Wu Lianfeng's laboratory.

Wu Lianfeng still remembers the situation of visiting his laboratory the day before the school: wearing a helmet in the door, not even the window. After half a year of school, his team did experiments in his laboratory.

In the early days of entrepreneurship, Wu Lianfeng had never shaken Wu Lianfeng's confidence. As a member of the party, he has more responsibilities of the first soldier: the school has just faced such difficulties. As a pioneer, the way must be more difficult than difficulties.

After the start of the school but the laboratory was still under construction, Wu Lianfeng ran away. With the help of schools, West Lake District and scientific research colleagues, he and his colleagues borrowed the laboratory of other universities and companies to carry out experiments in time. Delaying scientific research progress.

Reporter Wei Zhiyang photographed friends Ma Chongyan

"After the first difficulty, my first independent laboratory, quickly possessed the world's first -class hardware. With talents attracting talents, scientific research elites from all over the world continue to join the team." Wu Lianfeng said.

In the past five years, the talent team of the School of Life Sciences has increased from three to more than 70. "All those who come to the college are all first -class talents in the world, and 90%of them have received the offer." Wu Lianfeng, a member of the college recruitment committee, witnessed the influx of talents. This is also the decisive factor in scientific research at the forefront of the world.

Scientific research is only first, no second. Basic research is long -term, large investment, and difficulty, and often requires the spirit of "ten years of grinding a sword". The 15 -person Wu Lianfeng Laboratory team was unremittingly worked out of the fog in the field of metabolism and aging. Failure is a commonplace, but every time it is successful is a breakthrough in the "uninhabited area" of scientific research.

Just recently, after 5 years of continuous and continuous harsh scientific experiments and reasoning, Wu Lianfeng Lab has published the latest research results in the well -known academic journal "Cell Report" ("Cell Report") in the global life sciences. The paper explains the phenomenon of the early life of vitamin B12 that affects the adult metabolism and reproductive characteristics of the organism, as well as the molecular mechanism of its cross -time airspace.

"We use nematodes as a model. At the molecular level, we reveal the metabolic disorders caused by the lack of vitamin B12 at the molecular level. The early origin characteristics of the early origin." Wu Lianfeng said. In layman's terms, this research results suggest that if a person has metabolic diseases such as obesity, diabetes, polycystic ovarian syndrome in adulthood, it may be related to the lack of vitamin B12 when he was a child. This provides new ideas for clinical studies of related diseases.

More than that. Why can diabetic drugs and dual -dual -dual -dual -dual -dual pheasant resistance and anti -aging, how to kill tumor cells in natural immunocononial molecular molecular granurase ... Faced with the problems that trouble metabolic diseases after another, Wu Lianfeng led a series of research results from the molecular mechanism level. The new understanding and even effective tools provide basic research support for finding better metabolic disease treatment drugs.

Reporter Wei Zhiyang photographed friends Ma Chongyan

In recent years, with the efforts of domestic scientific researchers, well -known scientific research journals including "Nature" and "Cell" have invested more and more attention to Chinese scientific researchers. "Not long ago, a editor of" Nature "talked to me and said that he hoped to come to Western Lake University because this new school frequently appeared in the submission. West Lake University is the epitome of the rise of scientific research in Zhejiang and China." Wu Lianfeng said. "In Zhejiang, in China, the scientific research ecology is constantly optimizing, and the team that challenges the peak of scientific research has continued to grow." Wu Lianfeng said happily. Ten years ago, in the field of metabolism and aging research, domestic independent laboratories were relatively small. Today, there are two or three hundred domestic independent laboratories in his familiar international academic group.

As a science and technology worker, after becoming a representative of the 20th National Congress of the Communist Party of China, he felt that the responsibility of his shoulders became more heavy.

"In addition to taking the lead in scientific research to overcome difficulties, I also have to do a good job of bridge and focus on the trends and development issues in the research field. I hope to bring the voice of the scientific and technological circles to Beijing." Wu Lianfeng said.

As the party's twenty steps approached, Wu Lianfeng hurriedly visited scientific research coffee, professors of various colleges, and heads of laboratories to listen to opinions and suggestions. The innovative environment and talent policy of scientific researchers are in his theme of his interview. In addition, he also wanted to feel the support of scientific research in all sectors of society in Zhejiang in Zhejiang, and brought him the development story of him and West Lake University to the conference.

"It is happy to encounter such a good environment when I return to work. I am grateful, and I will not forget my original intention. Leading the team to create more value for the society with scientific research." Wu Lianfeng said.

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