The first Chinese medicine treatment of painful diabetes peripheral neuropathy RCT research was published in international well -known journals

Author:Guangdong Provincial Hospital Time:2022.09.09

Recently, the endocrinology team of Fangcun Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine Hospital published research results in the international well-known journal "Journal of Diabetes" (2022 Chinese Academy of Sciences, IF: 4.530). , Single-Blind, Double-Dummy, and Parallel Controlled Clinical Trial "

With the funding of the special fund of traditional Chinese medicine science and technology research on traditional Chinese medicine in Guangdong Province, the endocrine team of Fangcun Hospital carried out the RCT study of the Chinese medicine "thirst and pain" VS Western medicine Pedibarin, and the treatment of painful diabetic peripheral neuropathy (PDPN). turn out:

(1) "Salmonic and Pain Fang" can significantly improve the pain score, which is equivalent to Western medicine Primalin, good safety;

(2) In terms of the improvement of patients' conscious symptoms, the "thirst and pain" is better than Prybalein;

(3) The neurotransmitting speed is reduced after treatment, and the "thirst and pain" has a potential effect of improving nerve conduction speed.

In addition, after two years of follow -up data, the research group prompts the "thirst and pain prescription" has a good long -term effect. The study is the first clinical trial of random, single -blindness, dual simulation, and parallel control at home and abroad. It aims to evaluate the efficacy and safety of Chinese medicine for patients with diabetic pain in diabetes.

Pain diabetes peripheral neuropathy (PDPN) is a common complication of diabetes, with a incidence of 22%. The clinical manifestation is physical symmetry pain, or like knife cutting, burning, acupuncture, often accompanied Affecting the quality of life of patients is a major problem in the current field of neural pain, and Pulaibalin recommended first -line medication for international guidelines, but due to its various adverse reactions, such as dizziness, drowsiness, increased suicide behavior and ideas, restricted restrictions, restrictions on restrictions. Its clinical application.

Under the leadership of Professor Fan Guanjie, director of the Department of Endocrinology of the Hospital, Liu Zhenjie, Director Liu Zhenjie, the Department of Endocrinology of Fangcun Hospital, has long been committed to the clinical and scientific research of PDPN in TCM therapy. "Pain Fang" has cured a large number of patients with PDPN, and the clinical efficacy is exactly the exact effect, and the national invention patent has been obtained. A series of scientific research on the PDPN team carried out a series of scientific research: the cause of PDPN through the method of case control, and the evidence -based studies on PDPN risk factors; ; From different research perspectives, the clinical efficacy of RCT research and evaluation is designed. The team is committed to the research of evidence -based medical research, giving play to the advantages of traditional Chinese medicine, and striving to break through the treatment difficulties of PDPN.

Supply: Li Anxiang, Fangcun Hospital, Fangcun Hospital, Guangdong Province

Executive editor: Wu Yuan Tuan

Audit school pair: Zhuang Yingge

Editor in charge: Song Liping

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