[Popular science] Long -term eaten Omeprazole, beware of heart, liver and kidney function damage

A few days ago, a 70 -year -old gentleman came to the hospital for examination and found that severe liver and kidney damage occurred. According to Mr. Lao, because of stomach problems, he has often taken Omeprazole for more than ten years. This is a typical case of drug -derived liver and kidney damage. I would like to remind everyone: We must take it safely and reasonably!

Why eat Omeprazole?

Anti -acidity, nausea, "burning heart", hurry up to eat Omeprazole. This is a common choice for many patients with stomach diseases. Almost any stomach disease takes Omeprazole for a while.

Omeprazole is one of the proton pump inhibitors that suppress gastric acid secretion. When the gastric acid secretion is too much, the phenomenon of swallowing, nausea, and vomiting acid will occur. At this time, Omeprazole can come in handy.

Diseases with excessive gastric acid, including digestive ulcers, stress ulcers, gastroesophageal reflux, gastrointestinal mucosal damage, etc., can be treated and prevented with Omeprazole.

Generally speaking, the treatment of gastric ulcers with proton pump inhibitors such as omeprazole is usually 6 to 8 weeks; the treatment of duodenal ulcers is 4 to 6 weeks; Essence

Therefore, clinically, omeprazole is a good medicine for gastric disease.

What are the hazards of omeprazole?

However, don't forget that, like any medicine, Omeprazole also has its own adaptation. Long -term use, excessive use, and abuse will not only produce side effects, but may even cover up early cancer signals and delay treatment. There are three types of hazards for long -term eaten omeprazole:

Affects liver and kidney function. The metabolism of Omeprazole in the human body mainly depends on the role of the liver, and at the same time has a certain burden on the kidneys. Therefore, long -term eaten Omeprazole can cause liver and kidney damage. Those with severe liver and kidney function should be cautious.

Affect the digestive system. For long -term eaten octoprazole, gastric acid secretion is excessively suppressed, and the sterilization of gastric acid is weakened. When a large amount of harmful bacteria enters the intestine, it may destroy the balance of intestinal flora, causing symptoms such as constipation, diarrhea, abdominal pain, bloating, and bad breath.

Increase the risk of fracture. Especially for middle -aged and elderly people, long -term use of Omeprazole will cause calcium loss, cause osteoporosis, and increase risk of fracture. Because Omeprazole will affect the absorption of calcium and hinder calcium and phosphorus metabolism.

In addition, long -term eaten omeprazole may also cause neurological disorders and atrophic gastritis.

What should I pay attention to when taking Omeprazole?

Omeprazole is also a prescription medicine. It cannot be bought casually. It should be used reasonably under the guidance of a doctor. During the medication, you should pay attention to the following points:

Take treatment (short -term). The medication is still not solved by the specified treatment. Be sure to find a doctor for consultation or diagnosis and treatment again.

Don't adjust the amount of medication by yourself. The appropriate drug dose is the key to treating the disease. If the dose is small, it will affect the treatment effect. If the dose is large, it will increase the risk.

Mix with other drugs with caution. Omeprazole will also affect the absorption or metabolism of certain drugs. If it will increase the absorption of aspirin, Jetin, nonopenzine, reduce the absorption of drugs such as clopidogre, bomonetllisone, etc. If mixed, it will affect other drugs The effect may even have serious problems.

Special people should use it with caution or disability. Elderly (especially osteoporosis), children, and poor resistance should be used with caution. Infants, pregnant women, lactating women, and severe liver and kidney dysfunction must be disabled.

Pay attention to the best time and method of medication. Under normal circumstances, the effect of taking medicine 30 minutes before meals is the best. Take or divide it in the morning or twice in the morning. Do not chew the intestinal soluble agent.

Adverse reactions occur in time. If the symptoms are not serious, you can decide whether to continue after observation. If a rash appears after taking Omeprazole, he should stop the medicine immediately and consult the doctor in time.

In short, Omeprazole is a prescription medicine. There are certain hazards and risks in long -term use. You must follow the doctor's advice and reasonable medication.

Author: Xinyang Central Hospital Gastrointestinal Medicine Jinyang

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